1. of the universe; very large.   Hint First letter clue   2. cross-bred or mongrel.   First letter clue   3. periodic shedding (of leaves).   First letter clue   4. surgically sterile or preventing infection.   First letter clue   5. having a fixed order or nature.   First letter clue   6. flesh-eating.   First letter clue   7. spread around like a gas; verbose.   First letter clue