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DNA Replication


This quiz is based on the process of DNA replication in both Prokaryotes and Eukaryotes.

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Multiple choice

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1.

A repeating DNA sequence at the end of chromosomes that prevents them from losing base pair sequences at their ends and from fusing together is called :

  A Telomere

  A Telomerase

  A replicon

  None of the above.

  Half-n-half Clue
 

2.

The enzyme that (during replication) proceeds along one of the strands of a DNA molecule adding deoxy-nucleotide-triphosphates to hydrogen bond with their appropriate complementary dNTP on the other single strand and to form a covalent phosphodiester bond with the previous nucleotide of the same strand is called :

  DNA Polymerase II

  Primase

  DNA Polymerase III

  DNA Polymerase I

  Half-n-half Clue
 

3.

The enzyme (made of proteins and RNA) that elongates chromosomes by adding TTAGGG sequences to the end of existing chromosomes is :

  Telomerase

  Exonuclease

  Endonuclease

  Amylase

  Half-n-half Clue
 

4.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called :

  Replicon fragments

  Okazaki fragments

  Klenow fragments

  None of the above

  Half-n-half Clue
 

5.

DNA Polymerase III is actually an aggregate of several different protein subunits. So it is often called a :

  Holoenzyme

  Primeosome

  replisome

  None of the above

  Half-n-half Clue
 

6.

A mamalian cell typically has 1.2 meters (when completely outstretched) of double stranded DNA.The total time to duplicate the DNA is 5 hours. How many origins of replication are there if the rate of duplication is 16µmeters/min ?

  250

  15000

  1

  500

  Half-n-half Clue
 

7.

A major difference between DNA replication in prokaryotes and eukaryotes is :

  DNA amylase performs the function of DNA helicase in prokaryotes

  there is only one replication origin in prokaryotes.

  prokaryotes do not use Topoisomerase in the replication process

  replication is conservative in prokaryotes

  Half-n-half Clue
 


 
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