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DNA Replication


This quiz is based on the process of DNA replication in both Prokaryotes and Eukaryotes.

Formats Info Page Worksheet / Test Paper Quiz Review
Multiple choice

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1.

The enzyme that accomplishes the unwinding of the original double stranded DNA molecule, once supercoiling has been eliminated, by breaking the hydrogen bonds that hold the two strands together is :

  Topoisomerase

  Primase

  Helicase

  DNA Polymerase II

  Half-n-half Clue
 

2.

The enzyme that (during replication) proceeds along one of the strands of a DNA molecule adding deoxy-nucleotide-triphosphates to hydrogen bond with their appropriate complementary dNTP on the other single strand and to form a covalent phosphodiester bond with the previous nucleotide of the same strand is called :

  Primase

  DNA Polymerase I

  DNA Polymerase III

  DNA Polymerase II

  Half-n-half Clue
 

3.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called :

  Replicon fragments

  Okazaki fragments

  Klenow fragments

  None of the above

  Half-n-half Clue
 

4.

A mamalian cell typically has 1.2 meters (when completely outstretched) of double stranded DNA.The total time to duplicate the DNA is 5 hours. How many origins of replication are there if the rate of duplication is 16µmeters/min ?

  250

  15000

  1

  500

  Half-n-half Clue
 

5.

The enzyme that creates a short RNA oligonucleotide at initiation sites where replication is to be carried out is called :

  Primase

  DNA Ligase

  DNA Gyrase

  Exonuclease

  Half-n-half Clue
 

6.

The enzyme (made of proteins and RNA) that elongates chromosomes by adding TTAGGG sequences to the end of existing chromosomes is :

  Telomerase

  Exonuclease

  Endonuclease

  Amylase

  Half-n-half Clue
 

7.

What does transformation involve in Bacteria ?

  the creation of a strand of DNA from RNA

  assimilation of external DNA into a cell

  the creation of a strand of RNA from DNA

  the infection of cells by a phage DNA molecule

  Half-n-half Clue
 


 
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