1. A mamalian cell typically has 1.2 meters (when completely outstretched) of double stranded DNA.The total time to duplicate the DNA is 5 hours. How many origins of replication are there if the rate of duplication is 16µmeters/min ?   250   15000   1   500   Hint Half-n-half Clue   2. A major difference between DNA replication in prokaryotes and eukaryotes is :   prokaryotes do not use Topoisomerase in the replication process   there is only one replication origin in prokaryotes.   replication is conservative in prokaryotes   DNA amylase performs the function of DNA helicase in prokaryotes   Half-n-half Clue   3. The end of a DNA strand that has a phosphate group attached to the number 5 carbon of its terminal deoxyribonucleotide is called :   The 5 prime end (5')   The 3 prime end (3')   N-Terminus   C-Terminus   Half-n-half Clue   4. The enzyme that replaces the nucleotides of the RNA primer with the appropriate DNA nucleotides is :   DNA Polymerase II   RNA Polymerase   DNA Ligase   DNA Gyrase   Half-n-half Clue   5. In DNA, mutations at G-C sequences occur quite frequently since 5-methyl cytosine easily deaminates to form :   Thymine   Adenine   Guanine   Cytosine   Half-n-half Clue   6. Which of the following agents is not a mutagen ?   Ultraviolet radiation   A retrovirus   A transposon or jumping gene   None of the above   Half-n-half Clue   7. The enzyme X removes RNA primers attached by Primase and this gap is then filled in by DNA Polymerase I. The enzyme X is :   RNase H   DNA amylase   DNA ligase   Reverse Transcriptase   Half-n-half Clue