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DNA Replication


This quiz is based on the process of DNA replication in both Prokaryotes and Eukaryotes.

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Multiple choice

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1.

Because DNA polymerase III can only act from 5' to 3', continuous strand growth can be achieved only along one of the template strands (Leading strand) and strand growth along the other strand must occur discontinuously resulting in the production of a series of short sections of new DNA called :

  Replicon fragments

  Okazaki fragments

  Klenow fragments

  None of the above

  Half-n-half Clue
 

2.

The enzyme that stitches Okazaki fragments together (along the lagging strand) is called :

  Topoisomerase

  DNA Polymerase II

  DNA Ligase

  Holoenzyme

  Half-n-half Clue
 

3.

DNA Polymerase III is actually an aggregate of several different protein subunits. So it is often called a :

  Holoenzyme

  Primeosome

  replisome

  None of the above

  Half-n-half Clue
 

4.

The enzyme responsible for initiating the unwinding of double-stranded DNA (eliminating supercoiling) by nicking a single strand of the DNA molecule is :

  Ligase

  Helicase

  Gyrase

  Topoisomerase

  Half-n-half Clue
 

5.

The end of a DNA strand that has a phosphate group attached to the number 5 carbon of its terminal deoxyribonucleotide is called :

  The 5 prime end (5')

  The 3 prime end (3')

  N-Terminus

  C-Terminus

  Half-n-half Clue
 

6.

A repeating DNA sequence at the end of chromosomes that prevents them from losing base pair sequences at their ends and from fusing together is called :

  A Telomere

  A Telomerase

  A replicon

  None of the above.

  Half-n-half Clue
 

7.

A mamalian cell typically has 1.2 meters (when completely outstretched) of double stranded DNA.The total time to duplicate the DNA is 5 hours. How many origins of replication are there if the rate of duplication is 16µmeters/min ?

  250

  15000

  1

  500

  Half-n-half Clue
 


 
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